Quartz Crystal Microbalance.
Mass change and electrochemistry
The Quartz Crystal Microbalance is an instrument dedicated to the detection of surface modification occurring on a coated quartz crystal. It can be used to detect mass changes during electrodeposition or corrosion of a metallic sample, but also to detect SAM (Self-Assembled Monolayers), particles and other cells and biological bodies.
The BluQCM systems allow a real-time and sensitive monitoring of surface-bound interactions, such as adsorption and desorption processes, characterization of molecular interactions, protein conformational changes and electrochemically-driven mass changes. The BluQCM technology is based on the acoustic wave sensing principle, which enables an accurate detection of mass and structural changes on the sensor surface via dissipation measurements. The system can be coupled to a BioLogic potentiostat/galvanostat system to perform electrochemical QCM measurements. The platforms are versatile, allowing the use of different types of acoustic wave sensors, including up to 150 MHz High Fundamental Frequency (HFF) sensors and 5 MHz to 10 MHz sensors. The platforms also include high accuracy temperature and flow control for applications sensitive to temperature and requiring the renewal of liquid medium.
The BluQCM products exist in single and multichannel versions: BluQSD for single-channel and BluQMD for multichannel.
Both instruments allow dissipation determination and measurements at multiple overtones for a comprehensive description of the properties of the surface.